Iontophoresis is a non invasive permeation enhancement technique designed to improve the delivery rate of compounds across biological membranes. The technique generates an electrical potential gradient that facilitates the movement of solute ions across the membrane. Iontophoresis has been used greatest success in therapy of hyperhidrosis. Because of their charged nature and relatively large molecular size, iontophoresis may provide means for their effective delivery. This review discusses the advantages of iontophoresis which makes it suitable for transdermal delivery of drugs. The review also describe the basic mechanisms, various pathways etc for the successive and effective delivery of drugs across the skin with greater bioavailability. The Review gives tabular description of various iontophoretic research.
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